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A critical assessment of the role of helical intermediates in amyloid formation by natively unfolded proteins and polypeptides
Amyloidogenic proteins and polypeptides can be divided into two structural classes, namely those which are flexible and are intrinsically disordered in their unaggregated state and those which form a compact globular structure with a well-defined tertiary fold in their normally soluble state. This r...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719502/ https://ncbi.nlm.nih.gov/pubmed/19596696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzp036 |
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