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Recognition of atypical 5' splice sites by shifted base-pairing to U1 snRNA

Accurate pre-mRNA splicing is critical for gene expression. The 5' splice site (5' ss) — the highly diverse element at the 5' end of introns — is initially recognized via base-pairing to the 5' end of U1 small nuclear RNA (snRNA). However, many natural 5' ss have a very poor...

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Bibliografski detalji
Glavni autori: Roca, Xavier, Krainer, Adrian R
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719486/
https://ncbi.nlm.nih.gov/pubmed/19169258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1546
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