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Extended base pair complementarity between U1 snRNA and the 5′ splice site does not inhibit splicing in higher eukaryotes, but rather increases 5′ splice site recognition

Spliceosome formation is initiated by the recognition of the 5′ splice site through formation of an RNA duplex between the 5′ splice site and U1 snRNA. We have previously shown that RNA duplex formation between U1 snRNA and the 5′ splice site can protect pre-mRNAs from degradation prior to splicing....

詳細記述

保存先:
書誌詳細
主要な著者: Freund, Marcel, Hicks, Martin J., Konermann, Carolin, Otte, Marianne, Hertel, Klemens J., Schaal, Heiner
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201333/
https://ncbi.nlm.nih.gov/pubmed/16155183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki824
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