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Effects of Atypical κ-Opioid Receptor Agonists on Intrathecal Morphine-Induced Itch and Analgesia in Primates

Itch/pruritus is the most common side effect associated with spinal administration of morphine given to humans for analgesia. The aim of this study was to investigate the effectiveness of κ-opioid receptor (KOR) agonists with diverse chemical structures as antipruritics and to elucidate the receptor...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Ko, Mei-Chuan, Husbands, Stephen M.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Pharmacology and Experimental Therapeutics 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2719014/
https://ncbi.nlm.nih.gov/pubmed/18842704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.143925
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