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Distinct functions of opioid-related peptides and gastrin-releasing peptide in regulating itch and pain in the spinal cord of primates

How neuropeptides in the primate spinal cord regulate itch and pain is largely unknown. Here we elucidate the sensory functions of spinal opioid-related peptides and gastrin-releasing peptide (GRP) in awake, behaving monkeys. Following intrathecal administration, β-endorphin (10–100 nmol) and GRP (1...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, Heeseung, Ko, Mei-Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4483774/
https://ncbi.nlm.nih.gov/pubmed/26119696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep11676
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