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Effects of Atypical κ-Opioid Receptor Agonists on Intrathecal Morphine-Induced Itch and Analgesia in Primates
Itch/pruritus is the most common side effect associated with spinal administration of morphine given to humans for analgesia. The aim of this study was to investigate the effectiveness of κ-opioid receptor (KOR) agonists with diverse chemical structures as antipruritics and to elucidate the receptor...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Pharmacology and Experimental Therapeutics
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2719014/ https://ncbi.nlm.nih.gov/pubmed/18842704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.143925 |
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