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The Differential Binding and Activity of PRO 2000 Against Diverse HIV-1 Envelopes
OBJECTIVE: PRO 2000 is a polyanionic microbicide that binds directly to the gp120 envelope protein to inhibit HIV-1 entry. We studied the breadth of PRO 2000 activity against HIV-1 derived from recently transmitted R5 viruses. We also investigated the interaction of this compound with X4 and R5 HIV-...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2718789/ https://ncbi.nlm.nih.gov/pubmed/19349871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e31819f9e31 |
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