The use of immune complex vaccines to enhance antibody responses against neutralizing epitopes on HIV-1 envelope gp120

The capacity of immune complexes to augment antibody (Ab) responses is well established. The enhancing effects of immune complexes have been attributed mainly to Fc-mediated adjuvant activity, while the ability of Abs to induce antigenic alterations of specific epitopes as a result of immune complex...

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Main Authors: Hioe, Catarina E., Visciano, Maria Luisa, Kumar, Rajnish, Liu, Jianping, Mack, Ethan A., Simon, Rachel E., Levy, David N., Tuen, Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2789659/
https://ncbi.nlm.nih.gov/pubmed/19879224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.10.040
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