The TCL1A Oncoprotein Interacts Directly with the NF-κB Inhibitor IκB

The T cell leukaemia/lymphoma 1A (TCL1A) oncoprotein plays key roles in several B and T cell malignancies. Lacking enzymatic activity, TCL1A's transforming action was linked to its capacity to co-activate the protein kinase AKT via binding to its pleckstrin homology (PH) domain. However, pertur...

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Bibliographic Details
Main Authors: Ropars, Virginie, Despouy, Gilles, Stern, Marc-Henri, Benichou, Serge, Roumestand, Christian, Arold, Stefan T.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718698/
https://ncbi.nlm.nih.gov/pubmed/19668332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006567
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