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Tcl1 interacts with Atm and enhances NF-κB activation in hematologic malignancies
The T-cell leukemia/lymphoma 1 (TCL1) oncogene is a target of chromosomal translocations and inversions at 14q31.2, and its rearrangement in T cells causes T-cell prolymphocytic leukemias. TCL1 dysregulation in B cells is responsible for the development of an aggressive form of chronic lymphocytic l...
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Main Authors: | , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
American Society of Hematology
2012
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251228/ https://ncbi.nlm.nih.gov/pubmed/22065599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-08-374561 |
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