Tcl1 interacts with Atm and enhances NF-κB activation in hematologic malignancies

The T-cell leukemia/lymphoma 1 (TCL1) oncogene is a target of chromosomal translocations and inversions at 14q31.2, and its rearrangement in T cells causes T-cell prolymphocytic leukemias. TCL1 dysregulation in B cells is responsible for the development of an aggressive form of chronic lymphocytic l...

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Autors principals: Gaudio, Eugenio, Spizzo, Riccardo, Paduano, Francesco, Luo, Zhenghua, Efanov, Alexey, Palamarchuk, Alexey, Leber, Amanda S., Kaou, Mohamed, Zanesi, Nicola, Bottoni, Arianna, Costinean, Stefan, Rassenti, Laura Z., Nakamura, Tatsuya, Kipps, Thomas J., Aqeilan, Rami I., Pekarsky, Yuri, Trapasso, Francesco, Croce, Carlo M.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2012
Matèries:
Lymphoid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251228/
https://ncbi.nlm.nih.gov/pubmed/22065599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-08-374561
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