Epigenetic roles of MLL oncoproteins are dependent on NF-κB

MLL fusion proteins in leukemia induce aberrant transcriptional elongation and associated chromatin perturbations, however the upstream signaling pathways and activators that recruit or retain MLL oncoproteins at initiated promoters are unknown. Through functional and comparative genomic studies, we...

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Detalhes bibliográficos
Main Authors: Kuo, Hsu-Ping, Wang, Zhong, Lee, Dung-Fang, Iwasaki, Masayuki, Duque-Afonso, Jesus, Wong, Stephen H.K., Lin, Chiou-Hong, Figueroa, Maria E., Su, Jie, Lemischka, Ihor R., Cleary, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816582/
https://ncbi.nlm.nih.gov/pubmed/24054986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2013.08.019
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