Epigenetic roles of MLL oncoproteins are dependent on NF-κB

MLL fusion proteins in leukemia induce aberrant transcriptional elongation and associated chromatin perturbations, however the upstream signaling pathways and activators that recruit or retain MLL oncoproteins at initiated promoters are unknown. Through functional and comparative genomic studies, we...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kuo, Hsu-Ping, Wang, Zhong, Lee, Dung-Fang, Iwasaki, Masayuki, Duque-Afonso, Jesus, Wong, Stephen H.K., Lin, Chiou-Hong, Figueroa, Maria E., Su, Jie, Lemischka, Ihor R., Cleary, Michael L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816582/
https://ncbi.nlm.nih.gov/pubmed/24054986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2013.08.019
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