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Roscovitine reduces neuronal loss, glial activation and neurological deficits after brain trauma
TBI causes both direct and delayed tissue damage. The latter is associated with secondary biochemical changes such as cell cycle activation that lead to neuronal death, inflammation and glial scarring. Flavopiridol — a CDK inhibitor that is neither specific nor selective — is neuroprotective. To exa...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2718694/ https://ncbi.nlm.nih.gov/pubmed/18612315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2008.75 |
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