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Cell cycle inhibition provides neuroprotection and reduces glial proliferation and scar formation after traumatic brain injury

Traumatic brain injury (TBI) causes neuronal apoptosis, inflammation, and reactive astrogliosis, which contribute to secondary tissue loss, impaired regeneration, and associated functional disabilities. Here, we show that up-regulation of cell cycle components is associated with caspase-mediated neu...

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Hlavní autoři: Di Giovanni, Simone, Movsesyan, Vilen, Ahmed, Farid, Cernak, Ibolja, Schinelli, Sergio, Stoica, Bogdan, Faden, Alan I.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149422/
https://ncbi.nlm.nih.gov/pubmed/15923260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500989102
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