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Cell cycle inhibition provides neuroprotection and reduces glial proliferation and scar formation after traumatic brain injury

Traumatic brain injury (TBI) causes neuronal apoptosis, inflammation, and reactive astrogliosis, which contribute to secondary tissue loss, impaired regeneration, and associated functional disabilities. Here, we show that up-regulation of cell cycle components is associated with caspase-mediated neu...

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Detalhes bibliográficos
Main Authors: Di Giovanni, Simone, Movsesyan, Vilen, Ahmed, Farid, Cernak, Ibolja, Schinelli, Sergio, Stoica, Bogdan, Faden, Alan I.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1149422/
https://ncbi.nlm.nih.gov/pubmed/15923260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500989102
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