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Failure of α-Galactosylceramide to Prevent Diabetes in Virus-Inducible Models of Type 1 Diabetes in the Rat
BACKGROUND: α-Galactosylceramide (α-GalCer) is an invariant natural killer T (iNKT) cell ligand that prevents type 1 diabetes in NOD mice. However, α-GalCer can activate or suppress immune responses, raising concern about its potential use in human diabetes. MATERIALS AND METHODS: To evaluate this t...
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| Hoofdauteurs: | , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2009
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2718559/ https://ncbi.nlm.nih.gov/pubmed/19414403 |
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