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Ku86 represses lethal telomere deletion events in human somatic cells
Nonhomologous end joining (NHEJ), a form of DNA double-strand break (DSB) repair, is conserved from bacteria to humans. One essential NHEJ factor is Ku, which consists of a heterodimer of Ku70 and Ku86. In a plethora of model systems, null mutations for Ku70 or Ku86 present with defects in DNA DSB r...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2718384/ https://ncbi.nlm.nih.gov/pubmed/19581589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0903362106 |
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