Regulation of Telomere Length and Suppression of Genomic Instability in Human Somatic Cells by Ku86

Ku86 plays a key role in nonhomologous end joining in organisms as evolutionarily disparate as bacteria and humans. In eukaryotic cells, Ku86 has also been implicated in the regulation of telomere length although the effect of Ku86 mutations varies considerably between species. Indeed, telomeres eit...

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Main Authors: Myung, Kyungjae, Ghosh, Goutam, Fattah, Farjana J., Li, Gang, Kim, Haeyoung, Dutia, Amalia, Pak, Evgenia, Smith, Stephanie, Hendrickson, Eric A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2004
Teme:
DNA Dynamics and Chromosome Structure
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC416406/
https://ncbi.nlm.nih.gov/pubmed/15143195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.11.5050-5059.2004
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