Regulation of Telomere Length and Suppression of Genomic Instability in Human Somatic Cells by Ku86

Ku86 plays a key role in nonhomologous end joining in organisms as evolutionarily disparate as bacteria and humans. In eukaryotic cells, Ku86 has also been implicated in the regulation of telomere length although the effect of Ku86 mutations varies considerably between species. Indeed, telomeres eit...

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Detalhes bibliográficos
Main Authors: Myung, Kyungjae, Ghosh, Goutam, Fattah, Farjana J., Li, Gang, Kim, Haeyoung, Dutia, Amalia, Pak, Evgenia, Smith, Stephanie, Hendrickson, Eric A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC416406/
https://ncbi.nlm.nih.gov/pubmed/15143195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.11.5050-5059.2004
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