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Deletion of Ku86 causes early onset of senescence in mice
DNA double-strand breaks formed during the assembly of antigen receptors or after exposure to ionizing radiation are repaired by proteins important for nonhomologous end joining that include Ku86, Ku70, DNA-PK(CS), Xrcc4, and DNA ligase IV. Here we show that ku86-mutant mice, compared with control l...
Αποθηκεύτηκε σε:
Κύριοι συγγραφείς: | , , , , |
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Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
The National Academy of Sciences
1999
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC17958/ https://ncbi.nlm.nih.gov/pubmed/10485901 |
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