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Mutations to Ku Reveal Differences in Human Somatic Cell Lines
NHEJ (non-homologous end joining) is the predominant mechanism for repairing DNA double-stranded breaks in human cells. One essential NHEJ factor is the Ku heterodimer, which is composed of Ku70 and Ku86. Here we have generated heterozygous loss-of-function mutations for each of these genes in two d...
Tallennettuna:
| Päätekijät: | , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2008
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2427147/ https://ncbi.nlm.nih.gov/pubmed/18387344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.02.008 |
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