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Structural basis of transcription: Backtracked RNA polymerase II at 3.4 Å resolution

X-ray crystal structure determination of RNA polymerase II in the reverse translocated, or “backtracked” state completes the picture of the transcribing enzyme. The notable feature of the backtracked structure is a binding pocket for the first backtracked nucleotide, but no significant interaction w...

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Détails bibliographiques
Auteurs principaux: Wang, Dong, Bushnell, David A., Huang, Xuhui, Westover, Kenneth D., Levitt, Michael, Kornberg, Roger D.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718261/
https://ncbi.nlm.nih.gov/pubmed/19478184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1168729
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