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Atherosclerosis proceeds independently of thrombin-induced platelet activation in ApoE-/- mice

Platelet activation has long been postulated to contribute to the development of atherosclerotic plaques, although the mechanism by which this might occur remains unknown. Thrombin is a potent platelet activator and transfusion of thrombin-activated platelets into mice increases plaque formation, su...

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Detalhes bibliográficos
Main Authors: Hamilton, J.R., Cornelissen, I., Mountford, J.K., Coughlin, S.R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717183/
https://ncbi.nlm.nih.gov/pubmed/19217621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.atherosclerosis.2009.01.018
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