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Atherosclerosis in ApoE-deficient mice progresses independently of the NLRP3 inflammasome

The interleukin-1 (IL-1) family of cytokines has been implicated in the pathogenesis of atherosclerosis in previous studies. The NLRP3 inflammasome has recently emerged as a pivotal regulator of IL-1β maturation and secretion by macrophages. Little is currently known about a possible role for the NL...

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Detalhes bibliográficos
Main Authors: Menu, P, Pellegrin, M, Aubert, J-F, Bouzourene, K, Tardivel, A, Mazzolai, L, Tschopp, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3101814/
https://ncbi.nlm.nih.gov/pubmed/21451572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2011.18
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