Activation of NLRP3 inflammasomes contributes to hyperhomocysteinemia-aggravated inflammation and atherosclerosis in apoE-deficient mice

Hyperhomocysteinemia (HHcy) has been shown to promote vascular inflammation and atherosclerosis, but the underlying mechanisms remain largely unknown. The NLRP3 inflammasome has been identified as the cellular machinery responsible for activation of inflammatory processes. In this study, we hypothes...

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Detalhes bibliográficos
Publicado no:Lab Invest
Main Authors: Wang, Renqing, Wang, Yiqin, Mu, Nana, Lou, Xiaoying, Li, Weixuan, Chen, Yanming, Fan, Dong, Tan, Hongmei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5537437/
https://ncbi.nlm.nih.gov/pubmed/28394319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2017.30
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