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Role of NLRP3 Inflammasomes in Atherosclerosis

Inflammation with macrophage infiltration is a key feature of atherosclerosis. Although the mechanisms had been unclear, emerging evidence unveiled that NLRP3 inflammasomes, which regulate caspase-1 activation and subsequent processing of pro-IL-1β, trigger vascular wall inflammatory responses and l...

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Pubblicato in:J Atheroscler Thromb
Autori principali: Karasawa, Tadayoshi, Takahashi, Masafumi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Japan Atherosclerosis Society 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5429158/
https://ncbi.nlm.nih.gov/pubmed/28260724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5551/jat.RV17001
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