Human Neurospheres as Three-Dimensional Cellular Systems for Developmental Neurotoxicity Testing

BACKGROUND: Developmental neurotoxicity (DNT) of environmental chemicals is a serious threat to human health. Current DNT testing guidelines propose investigations in rodents, which require large numbers of animals. With regard to the “3 Rs” (reduction, replacement, and refinement) of animal testing...

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Bibliografiska uppgifter
Huvudupphovsmän: Moors, Michaela, Rockel, Thomas Dino, Abel, Josef, Cline, Jason E., Gassmann, Kathrin, Schreiber, Timm, Schuwald, Janette, Weinmann, Nicole, Fritsche, Ellen
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Institute of Environmental Health Sciences 2009
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717141/
https://ncbi.nlm.nih.gov/pubmed/19654924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.0800207
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