Species-Specific Differential AhR Expression Protects Human Neural Progenitor Cells against Developmental Neurotoxicity of PAHs

BACKGROUND: Because of their lipophilicity, persistent organic pollutants (POPs) cross the human placenta, possibly affecting central nervous system development. Most POPs are known aryl hydrocarbon receptor (AhR) ligands and activators of AhR signaling. Therefore, AhR activation has been suggested...

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Main Authors: Gassmann, Kathrin, Abel, Josef, Bothe, Hanno, Haarmann-Stemmann, Thomas, Merk, Hans F., Quasthoff, Kim N., Rockel, Thomas Dino, Schreiber, Timm, Fritsche, Ellen
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2010
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974695/
https://ncbi.nlm.nih.gov/pubmed/20570779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.0901545
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