IGF-1R Contributes to Stress-Induced Hepatocellular Damage in Experimental Cholestasis

The insulin-like growth factor type 1 receptor (IGF-1R) controls aging and cellular stress, both of which play major roles in liver disease. Stimulation of insulin-like growth factor signaling can generate cell death in vitro. Here, we tested whether IGF-1R contributes to stress insult in the liver....

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Detalhes bibliográficos
Main Authors: Cadoret, Axelle, Rey, Colette, Wendum, Dominique, Elriz, Khaldoun, Tronche, François, Holzenberger, Martin, Housset, Chantal
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2716962/
https://ncbi.nlm.nih.gov/pubmed/19628767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.081081
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