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From Synthesis to Biologics: Preclinical Data on a Chemistry Derived Anticancer Vaccine
A fully synthetic anticancer vaccine 2 has been prepared via bio-conjugation of unimolecular pentavalent construct 1 – containing five prostate and breast cancer associated carbohydrate antigens, Globo-H, GM2, STn, TF and Tn – to maleimide-modified carrier protein KLH. An improved conjugation protoc...
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| Asıl Yazarlar: | , , , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2009
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2716484/ https://ncbi.nlm.nih.gov/pubmed/19518111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja901415s |
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