A Phase I Study of Unimolecular Pentavalent (Globo-H-GM2-sTn-TF-Tn) Immunization of Patients with Epithelial Ovarian, Fallopian Tube, or Peritoneal Cancer in First Remission

We conducted a phase I study in ovarian cancer patients to evaluate the safety and immunogenicity of a synthetic unimolecular pentavalent carbohydrate vaccine (Globo-H, GM2, sTn, TF, and Tn) supported on a peptide backbone, conjugated to keyhole limpet haemocyanin (KLH), and mixed with immunological...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancers (Basel)
Main Authors: O’Cearbhaill, Roisin E., Ragupathi, Govind, Zhu, Jianglong, Wan, Qian, Mironov, Svetlana, Yang, Guangbin, Spassova, Maria K., Iasonos, Alexia, Kravetz, Sara, Ouerfelli, Ouathek, Spriggs, David R., Danishefsky, Samuel J., Sabbatini, Paul J.
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846855/
https://ncbi.nlm.nih.gov/pubmed/27110823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers8040046
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki