Загрузка...
Defective Histone Acetylation Is Responsible for the Diminished Expression of Cyclooxygenase 2 in Idiopathic Pulmonary Fibrosis
Diminished cyclooxygenase 2 (COX-2) expression in fibroblasts, with a resultant defect in the production of the antifibrotic mediator prostaglandin E(2), plays a key role in the pathogenesis of idiopathic pulmonary fibrosis (IPF). Here, we have characterized the molecular mechanism. We found that CO...
Сохранить в:
Главные авторы: | , , , , |
---|---|
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
American Society for Microbiology (ASM)
2009
|
Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715818/ https://ncbi.nlm.nih.gov/pubmed/19487460 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01776-08 |
Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|