Interplay between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis

Selective repression of the antifibrotic gene CXCL10 contributes to tissue remodeling in idiopathic pulmonary fibrosis (IPF). We have previously reported that histone deacetylation and histone H3 lysine 9 (H3K9) methylation are involved in CXCL10 repression. In this study, we explored the role of H3...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Coward, William R., Brand, Oliver J., Pasini, Alice, Jenkins, Gisli, Knox, Alan J., Pang, Linhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894498/
https://ncbi.nlm.nih.gov/pubmed/29053336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0286OC
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