Interplay between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis

Selective repression of the antifibrotic gene CXCL10 contributes to tissue remodeling in idiopathic pulmonary fibrosis (IPF). We have previously reported that histone deacetylation and histone H3 lysine 9 (H3K9) methylation are involved in CXCL10 repression. In this study, we explored the role of H3...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Respir Cell Mol Biol
Prif Awduron: Coward, William R., Brand, Oliver J., Pasini, Alice, Jenkins, Gisli, Knox, Alan J., Pang, Linhua
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Thoracic Society 2018
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5894498/
https://ncbi.nlm.nih.gov/pubmed/29053336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2017-0286OC
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