The K(+) Channel K(Ca)3.1 as a Novel Target for Idiopathic Pulmonary Fibrosis

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a common, progressive and invariably lethal interstitial lung disease with no effective therapy. We hypothesised that K(Ca)3.1 K(+) channel-dependent cell processes contribute to IPF pathophysiology. METHODS: K(Ca)3.1 expression in primary human lun...

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Main Authors: Roach, Katy Morgan, Duffy, Stephen Mark, Coward, William, Feghali-Bostwick, Carol, Wulff, Heike, Bradding, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877378/
https://ncbi.nlm.nih.gov/pubmed/24392001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085244
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