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Aggregatibacter actinomycetemcomitans Cytolethal Distending Toxin Induces Apoptosis in Nonproliferating Macrophages by a Phosphatase-Independent Mechanism

Aggregatibacter actinomycetemcomitans strains that express cytolethal distending toxin (Cdt) are associated with localized aggressive periodontitis. However, the in vivo targets of Cdt in the human oral cavity have not been firmly established. Here, we demonstrate that A. actinomycetemcomitans Cdt k...

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Detalles Bibliográficos
Main Authors: Rabin, Shira D. P., Flitton, Jared G., Demuth, Donald R.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715655/
https://ncbi.nlm.nih.gov/pubmed/19470743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01227-08
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