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Pharmacokinetics-Pharmacodynamics of Pyrazinamide in a Novel In Vitro Model of Tuberculosis for Sterilizing Effect: a Paradigm for Faster Assessment of New Antituberculosis Drugs

There are currently renewed efforts to develop drugs that could shorten the duration of antituberculosis therapy. This is best achieved by optimizing the sterilizing effect. However, the current pathway for the development of new molecules with the potential to have a sterilizing effect is inefficie...

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Bibliografiska uppgifter
Huvudupphovsmän: Gumbo, Tawanda, Siyambalapitiyage Dona, Chandima S. W., Meek, Claudia, Leff, Richard
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715614/
https://ncbi.nlm.nih.gov/pubmed/19451303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01681-08
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