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Pharmacokinetics-Pharmacodynamics of Pyrazinamide in a Novel In Vitro Model of Tuberculosis for Sterilizing Effect: a Paradigm for Faster Assessment of New Antituberculosis Drugs

There are currently renewed efforts to develop drugs that could shorten the duration of antituberculosis therapy. This is best achieved by optimizing the sterilizing effect. However, the current pathway for the development of new molecules with the potential to have a sterilizing effect is inefficie...

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Detalhes bibliográficos
Main Authors: Gumbo, Tawanda, Siyambalapitiyage Dona, Chandima S. W., Meek, Claudia, Leff, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715614/
https://ncbi.nlm.nih.gov/pubmed/19451303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01681-08
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