Stability of Peroxide Antimalarials in the Presence of Human Hemoglobin

Peroxide antimalarials, including artemisinin, are important for the treatment of multidrug-resistant malaria. These peroxides are known to react with iron or heme to produce reactive intermediates that are thought to be responsible for their antimalarial activities. This study investigated the pote...

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Bibliografiset tiedot
Päätekijät: Creek, Darren J., Ryan, Eileen, Charman, William N., Chiu, Francis C. K., Prankerd, Richard J., Vennerstrom, Jonathan L., Charman, Susan A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2009
Aiheet:
Mechanisms of Action: Physiological Effects
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715612/
https://ncbi.nlm.nih.gov/pubmed/19487440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00363-09
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