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Stability of Peroxide Antimalarials in the Presence of Human Hemoglobin

Peroxide antimalarials, including artemisinin, are important for the treatment of multidrug-resistant malaria. These peroxides are known to react with iron or heme to produce reactive intermediates that are thought to be responsible for their antimalarial activities. This study investigated the pote...

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Hlavní autoři: Creek, Darren J., Ryan, Eileen, Charman, William N., Chiu, Francis C. K., Prankerd, Richard J., Vennerstrom, Jonathan L., Charman, Susan A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715612/
https://ncbi.nlm.nih.gov/pubmed/19487440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00363-09
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