Comparative Antimalarial Activities of Six Pairs of 1,2,4,5-Tetraoxanes (Peroxide Dimers) and 1,2,4,5,7,8-Hexaoxonanes (Peroxide Trimers)

Six tetraoxanes had 50% inhibitory concentrations in the range of 10 to 100 ng/ml against Plasmodium falciparum, whereas the corresponding hexaoxonanes had minimal antimalarial activity. The lack of iron-mediated reactivity of the hexaoxonanes may explain their low activity compared to the tetraoxan...

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Detaylı Bibliyografya
Asıl Yazarlar: Dong, Yuxiang, Creek, Darren, Chollet, Jacques, Matile, Hugues, Charman, Susan A., Wittlin, Sergio, Wood, James K., Vennerstrom, Jonathan L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2007
Konular:
Susceptibility
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932524/
https://ncbi.nlm.nih.gov/pubmed/17485500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00264-07
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