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The virion-packaged endoribonuclease of herpes simplex virus 1 cleaves mRNA in polyribosomes

The virion host shutoff protein product of the U(L)41 gene of herpes simplex virus 1 is an endoribonuclease that selectively degrades mRNAs during the first hours after infection. Specifically, in contrast to the events in uninfected cells or cells infected with a mutant lacking the RNase, in wild-t...

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Bibliografiske detaljer
Main Authors: Taddeo, Brunella, Zhang, Weiran, Roizman, Bernard
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715532/
https://ncbi.nlm.nih.gov/pubmed/19584246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0905828106
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