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Protein-free small nuclear RNAs catalyze a two-step splicing reaction

Pre-mRNA splicing is a crucial step in eukaryotic gene expression and is carried out by a highly complex ribonucleoprotein assembly, the spliceosome. Many fundamental aspects of spliceosomal function, including the identity of catalytic domains, remain unknown. We show that a base-paired complex of...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Valadkhan, Saba, Mohammadi, Afshin, Jaladat, Yasaman, Geisler, Sarah
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: National Academy of Sciences 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2715495/
https://ncbi.nlm.nih.gov/pubmed/19549866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902020106
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