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Protein-free small nuclear RNAs catalyze a two-step splicing reaction
Pre-mRNA splicing is a crucial step in eukaryotic gene expression and is carried out by a highly complex ribonucleoprotein assembly, the spliceosome. Many fundamental aspects of spliceosomal function, including the identity of catalytic domains, remain unknown. We show that a base-paired complex of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2715495/ https://ncbi.nlm.nih.gov/pubmed/19549866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0902020106 |
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