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Protein-free spliceosomal snRNAs catalyze a reaction that resembles the first step of splicing
Splicing of introns from mRNA precursors is a two-step reaction performed by the spliceosome, an immense cellular machine consisting of over 200 different proteins and five small RNAs (snRNAs). We previously demonstrated that fragments of two of these RNAs, U6 and U2, can catalyze by themselves a sp...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Cold Spring Harbor Laboratory Press
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2080592/ https://ncbi.nlm.nih.gov/pubmed/17940139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.626207 |
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