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Protein-free spliceosomal snRNAs catalyze a reaction that resembles the first step of splicing
Splicing of introns from mRNA precursors is a two-step reaction performed by the spliceosome, an immense cellular machine consisting of over 200 different proteins and five small RNAs (snRNAs). We previously demonstrated that fragments of two of these RNAs, U6 and U2, can catalyze by themselves a sp...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Cold Spring Harbor Laboratory Press
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2080592/ https://ncbi.nlm.nih.gov/pubmed/17940139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.626207 |
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