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Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase
Glutathione (GSH) is a tripeptide composed of glutamate, cysteine, and glycine. The first and rate-limiting step in GSH synthesis is catalyzed by glutamate cysteine ligase (GCL, previously known as γ-glutamylcysteine synthetase). GCL is a heterodimeric protein composed of catalytic (GCLC) and modifi...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714364/ https://ncbi.nlm.nih.gov/pubmed/18812186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mam.2008.08.009 |
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