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Systematic identifiability testing for unambiguous mechanistic modeling – application to JAK-STAT, MAP kinase, and NF-κB signaling pathway models
BACKGROUND: When creating mechanistic mathematical models for biological signaling processes it is tempting to include as many known biochemical interactions into one large model as possible. For the JAK-STAT, MAP kinase, and NF-κB pathways a lot of biological insight is available, and as a conseque...
Uloženo v:
| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BioMed Central
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2714303/ https://ncbi.nlm.nih.gov/pubmed/19426527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-3-50 |
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