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IGF-IR tyrosine kinase interacts with NPM-ALK oncogene to induce survival of T-cell ALK(+) anaplastic large-cell lymphoma cells

Type I insulin-like growth factor receptor (IGF-IR) tyrosine kinase plays important roles in the pathogenesis of several malignancies. Although it promotes the growth of stimulated hematopoietic cells, a direct role of IGF-IR in malignant lymphoma has not been identified. Anaplastic lymphoma kinase-...

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Detalhes bibliográficos
Main Authors: Shi, Ping, Lai, Raymond, Lin, Quan, Iqbal, Abid S., Young, Leah C., Kwak, Larry W., Ford, Richard J., Amin, Hesham M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714211/
https://ncbi.nlm.nih.gov/pubmed/19423729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-11-125658
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