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Dual inhibition of IGF-IR and ALK as an effective strategy to eradicate NPM-ALK(+) T-cell lymphoma
BACKGROUND: Nucleophosmin-anaplastic lymphoma kinase-expressing (NPM-ALK(+)) T cell lymphoma is an aggressive neoplasm. NPM-ALK, an oncogenic tyrosine kinase, plays a critical role in this lymphoma. Recently, selective ALK inhibitors have emerged as a first-line therapy for this neoplasm. Unfortunat...
Shranjeno v:
| izdano v: | J Hematol Oncol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2019
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6657048/ https://ncbi.nlm.nih.gov/pubmed/31340850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-019-0768-8 |
| Oznake: |
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