IL-10 is up-regulated in multiple cell types during viremic HIV infection and reversibly inhibits virus-specific T cells

Murine models indicate that interleukin-10 (IL-10) can suppress viral clearance, and interventional blockade of IL-10 activity has been proposed to enhance immunity in chronic viral infections. Increased IL-10 levels have been observed during HIV infection and IL-10 blockade has been shown to enhanc...

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מידע ביבליוגרפי
Main Authors: Brockman, Mark A., Kwon, Douglas S., Tighe, Daniel P., Pavlik, David F., Rosato, Pamela C., Sela, Jennifer, Porichis, Filippos, Le Gall, Sylvie, Waring, Michael T., Moss, Kristin, Jessen, Heiko, Pereyra, Florencia, Kavanagh, Daniel G., Walker, Bruce D., Kaufmann, Daniel E.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Hematology 2009
נושאים:
Immunobiology
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2714209/
https://ncbi.nlm.nih.gov/pubmed/19365081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-12-191296
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